A number of drugs are being investigated for treatment and prevention of Alzheimer's disease. Intense areas of research are focusing on drugs that prevent or reduce beta amyloid build-up.
Drugs in late-stage clinical trials include:
- Bapineuzumab is an anti-beta amyloid monoclonal antibody drug being studied as a treatment for patients with mild-to-moderate Alzheimer's disease. It is currently in Phase III trials.
- Dimebon is an antihistamine that may help improve the course of the disease. It is being studied in combination with donepezil in patients with mild-to-moderate Alzheimer's disease. The drug is currently in Phase III trials.
- PBT2 is a drug designed to stop the formation of beta-amyloid plaques. It is being studied in patients with early-stage Alzheimer's disease and is currently in Phase II trials.