Researchers continue to search for imaging biomarkers that can predict who will develop Alzheimer's.
Positron emission tomography (PET) imaging of brain beta-amyloid is increasingly used in research for detecting early stages of Alzheimer's.
FDG-PET imaging was a more reliable tool than a commonly used cognitive test for monitoring Alzheimer's progression
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The 2 pathologic hallmarks of Alzheimer disease are
- Extracellular beta-amyloid deposits (in senile plaques)
- Intracellular neurofibrillary tangles (paired helical filaments)
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Cholinesterase inhibitors (donepezil (Aricept®), rivastigmine (Exelon®), galantamine (Razadyne®/Reminyl®)) can help manage Alzheimer's, but they do not cure or reverse the course of AD.
Memantine (Namenda®) has been approved for the treatment of moderate-severe AD.
A variety of medications are prescribed, with variable success, for psychiatric behavioral problems associated with AD and other dementia.
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Genetics of AD
Epidemiology of AD
Common causes of AD
Molecular Roots of AD
Signs & symptoms of AD
Types of AD
Prevention of AD
Testing for AD
Treatment for AD
Symptoms of AD
Evaluation of AD
Life Expectancy of AD