Adult T cell leukemia/lymphoma (ATLL) is a neoplasm of CD4 + T cells, caused by human T cell lymphotrophic virus I (HTLV-I), manifested by skin infiltrates, hypercalcemia, visceral involvement, lytic bone lesions, and abnormal lymphocytes on the peripheral smears.
* Generally the risk of NHL increases with advancing age. HL in the elderly is associated with a poorer prognosis than that observed in younger patients.
* Black hair dye, which for more than 20 years has been linked to higher rates of NHL.
* Inherited immunodeficiency diseases (severe combined immunodeficiency, ataxia telangiectasia, among a host of others)
* Viruses -- Human T-lymphotropic virus type I (HTLV-1) and Epstein-Barr virus are two infectious agents that increase the chance of developing non-Hodgkin's lymphoma.
* Lymph node swelling, often in the upper body area.
* A lack of energy, general fatigue.
* Weight loss
* Fevers which can come and go. ;
* Night sweats - unexplained sweating at night, often drenching
* Enlargement of the spleen may cause abdominal pain or discomfort.
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