An exanthematous drug reaction (eruption) is an adverse hypersensitivity reaction to an ingested or parenterally administered drug characterized by a cutaneous eruption that mimics a measles-like viral exanthem; systemic involvement is minimal.
Exact mechanism unknown. Probably delayed hypersensitivity. Rash with Epstein-Barr virus (EBV) and cytomegalovirus (CMV) mononucleosis probably not allergic.
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